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The least squares mean change compared to placebo is -10.7 with 4 mg retatrutide, -21.6 with 8 mg, and -18.7 with 12 mg

Cortisone shots are a synthetic hormone that closely resembles the stress hormone cortisol

Changing the tablet can affect how it is absorbed and may stop it from working properly

However, for individuals with severe obesity or obesity-related health conditions, surgery may be more effective in achieving rapid and significant weight loss

Staying hydrated and avoiding greasy or overly sweet foods also helps stabilize your digestive system while it adjusts to the medication's effects
