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Gln 19 GIP (130)-NH 2 , an active fragment of GIP with affinity and activity that align with those of integrated GIP, dramatically decreased somatostatinotropic activity in isolated perfused rat stomachs

Large meals can put pressure on the lower esophageal sphincter (LES), leading to an increased risk of reflux

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Nauck, M., Stockmann, F., Ebert, R

Your compounding pharmacy can adjust starting doses and titration speed based on your baseline GI tolerance

Gastrointestinal side effects represent another consideration