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It mimics the hormone GLP-1, which regulates hunger signals and feelings of satiety

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In a written response to Politiken, Novo Nordisk states that this is partly due to discussions about reimbursement for the medicine

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In contrast, long-acting GLP-1RAs, including liraglutide, dulaglutide, and semaglutide, demonstrated a more pronounced impact on nocturnal and fasting plasma glucose, as well as HbA1c, both when used alongside oral hypoglycemic agents and in combination with basal insulin

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Complementing these findings, a one-year randomized controlled trial by Villareal and colleagues demonstrated that obese older adults who achieved a 10.1% weight loss through combined diet and exercise experienced significant decreases in hip BMDincluding the trochanter and femoral neckwhile spine and whole-body BMD were preserved

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