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GLP-1 pharmacology The known physiological actions of GLP-1 indicate a great potential for its pharmacological use in obesity and DM treatment

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Clinical indications and expanding use Following fluoxetine, several SSRIs (e.g., sertraline, citalopram, and escitalopram) were introduced and are now established as first-line pharmacotherapies for major depressive disorder (MDD) and many anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder (OCD), and post-traumatic stress disorder) [6]

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doi: 10.3389/fendo.2018.00754 Received 31 October 2018 Accepted 27 November 2018 Published 04 January 2019 Volume 9 - 2018 Edited by Maximilian Bielohuby, Sanofi, France Reviewed by Yoshio Fujitani, Gunma University, Japan

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Table of Contents Introduction to GLP1 Receptor Agonists How GLP1 Might Influence Asthma What Animal Studies Tell Us Human Evidence: What We Know So Far What This Could Mean for Patients Future Research Needs Conclusion Frequently Asked Questions Introduction to GLP1 Receptor Agonists GLP1 is an incretin hormone that enhances insulin secretion, slows gastric emptying, and increases feelings of fullness

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Well, speaking of that heterogeneity, you've done a lot of work on obesity phenotypes, written a couple of books about it now a popular book, Six Factors to Fit , and now a book for clinicians to use this sort of obesity phenotype framework as part of treatment

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Actions of GLP-1 on exocrine pancreas Infusion of GLP-1 to mimic postprandial levels inhibits pancreatic exocrine secretion in response to intragastric infusion of a liquid meal in man (127)

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