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In the hypothalamus, GLP-1 promotes satiety and reduces hunger signals

This often leads to under-eating, which can cause nutrient deficiencies and also stalled weight loss as the body is trying to just survive on little calories

Diabetic retinopathy: Rapid improvements in glycaemic control as may occur with potent glucose-lowering agents have been associated with worsening of diabetic retinopathy in some patients

Also, anyone who appears to be under the influence of alcohol or drugs may not be able to donate since their condition might compromise their ability to give informed consent for the procedure

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Understanding how to protect your metabolic gains requires a combination of behavioral support, medical guidance, and potentially ongoing pharmaceutical intervention