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The gut microbial landscape can be significantly altered by confounding factors such the role of kidney failure per se [16], the large variations of dietary patterns worldwide, including animal or vegetable sources of food, antibiotic usage, and probiotic supplements, but few studies take these factors into account and many lack adequate controls [1, 6]

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However, the prior art did not disclose topical application to the sunburned or damaged skin, so the Federal Circuit found the prior art did not inherently anticipate the claims

Samuels MH, Kolobova I, Smeraglio A, Peters D, Purnell JQ, Schuff KG

They also show great promise for people with type 2 diabetes