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To identify the distribution and cell localization of GLP-1R in the TNC, we performed immunofluorescence staining

ANDREA TRAINA: As soon as you ingest food, your body is going to start secreting GLP-1 because it immediately triggers that, oh, you've ingested some food

Abbreviations The following abbreviations are used in this manuscript: Author Contributions Conceptualization and supervision, C.V

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Just as some foods enhance GLP-1, others may impair optimal GLP-1 signaling: Ultra-processed foods , engineered for rapid absorption, they bypass the slower nutrient-sensing mechanisms that trigger sustained GLP-1 release Refined carbohydrates , white bread, sugary cereals, and processed snacks cause rapid glucose spikes without the fiber, protein, or fat needed to sustain GLP-1 secretion High-saturated-fat meals , saturated fat appears to stimulate less GLP-1 than unsaturated fat, and high-saturated-fat diets are associated with impaired incretin signaling over time Alcohol , regular alcohol consumption is associated with disrupted gut hormone responses, including blunted GLP-1 secretion What is compound GLP-1, and is it safe