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Hoteit: Conceptualization

Among the drug classes under investigation for AD are the glucagon-like peptide-1 receptor agonists (GLP-1RAs), which are approved for the treatment of type 2 diabetes (T2D), obesity and cardiovascular disease

He has extensive experience in progressing compounds from hit-to-lead through to lead optimization and candidate selection in the fields of oncology, inflammation and CNS

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: A meta-analysis

Pearls and Quotes Clinical Implementation of GLP-1 Receptor Agonists GLP-1 agonists work through a variety of mechanisms to counteract metabolic disease

But gastric sleeve may be the better choice if: Your BMI qualifies you for bariatric surgery You want a a more durable tool You have significant obesity-related medical problems You are tired of the recurring cost of GLP-1 drugs You do not want to rely on indefinite injections You have lost and regained weight repeatedly on diets or medication You want a treatment with a stronger long-term track record For many patients with obesity, gastric sleeve is not a last resort. It is simply the most logical long-term treatment