glp 1 agonist vs analog Schematic representation of different GLP-1 analogues previously Science Behind GLP 1 GIP

3.10 Renal effects Exenatide has been associated with the development of acute kidney injury in about 100 case reports [140-146]

Phase 3 TRIUMPH-4 (topline) In Lillys topline summary, the most common adverse events included nausea, diarrhoea, constipation and vomiting (typical of incretin-based therapies)

Accessed: 2024-10-14

N Engl J Med 2017;377:1327.ArticlePubMedPMC 4

19 Jan 2017

Against this backdrop of investor exuberance, 2024 also delivered a dose of realism to temper runaway excitement about many novel AOM assets purported best-in-class profile, often based on nothing more than limited topline data from phase 1 trials