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The drugs are approved in Canada for diabetic treatment

Scientific References: Marathe CS, Rayner CK, Jones KL, Horowitz M

This is a real, clinically actionable signal that has been reported in trials independently of this analysis

Tirzepatide activates both, offering enhanced anti-inflammatory effects

The fate of taspoglutide, a weekly GLP-1 receptor agonist, versus twice-daily exenatide for type 2 diabetes: the T-emerge 2 trial

High gastrointestinal discontinuation rates exceeding 50% across all doses, combined with liver safety signals in early studies, ultimately led Pfizer to discontinue danugliprons development in April 2025
