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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

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Dr Reddy's to Miss FY27 Semaglutide Target of 12 Million Pens Due to API Quality Issue, Expects 6-7 Million Pens Instead The Shortfall Pharmaceutical major Dr Reddy's Laboratories (DRL) is set to miss its annual semaglutide production target of 12 million pens for FY27, due to

In-Use Storage: Once a cartridge is loaded into the pen and in use, you can keep it at room temperature (below 30C) or in the refrigerator for up to 30 days