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65,66 A network meta-analysis ranked SEMA 0.4 mg first in the resolution of MASH among alternative treatments [surface under the cumulative ranking (SUCRA) = 0.89], higher than liraglutide (SUCRA = 0.84) and resmetirom (SUCRA = 0.44)

Side effects should be minimal and manageable at this point

The debate surrounding GLP-1 medicines presents a remarkably similar challenge, but in a less visible context

2019;8(9):E1476

Novo argued that the proposed product was an unauthorized, untested version of semaglutide

First, supply is severely constrained as peptide manufacturing is expensive and requires billions of capital expenditure and years to build certified plants