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Semaglutide tends to be the better choice when you have established cardiovascular disease, when you want the longer safety track record, when you prefer or need an oral option, or when you value appetite-focused weight loss support with proven outcome data

Type 2 diabetes and obesity dramatically increase the risk of dementia by up to 60%, accelerating amyloid pathology, cerebrovascular damage, and insulin resistance in the brain, sometimes described as type 3 diabetes [1]

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In subsequent anterior cruciate ligament transection combined with medial meniscectomy rat studies, the team showed that liraglutide produced a strong antifibrotic effect, whereas dexamethasone had no measurable impact on fibrosis