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In general, semaglutide was more effective than other drugs in this category, and this effect looks to be dose-dependent, resulting in better weight loss when higher doses are used compared to lower doses in patients with obesity regardless of their diabetes status

Combination with Metformin or Metformin with Sulfonylurea In a 26-week, double-blind trial (Trial 3, NCT02607865), 1864 adult patients with type 2 mellitus diabetes on metformin alone or metformin with sulfonylurea were randomized to RYBELSUS 3 mg, RYBELSUS 7 mg, RYBELSUS 14 mg or sitagliptin 100 mg once daily

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doi: 10.1097/MLR.0b013e3181e35743 [DOI] [PubMed] [Google Scholar] 12.Sohn MW, Arnold N, Maynard C, Hynes DM

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In every news cycle, theres at least one story about GLP-1 drugs such as Ozempic, Wegovy and Zepbound