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In the first experiment, a total of 60 rats were divided equally into control, OA-1, OA-5, OA-10, OA-20 and OA-28 groups

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Treating obesity in type 1 diabetes mellitusreview of efficacy and safety

The index single-nucleotide polymorphism (SNP) of the main association was rs10305420 ( P = 2.9 10 10 , reference allele C, effect allele T), which conferred an additional 0.641% BMI loss per T allele, approximately equivalent to an additional 0.76 kg weight loss per allele (95% CI, [1.27, 0.34] kg)

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Food and Drug Administration (FDA)-approved label recommends 10 mcg twice daily after 1 month based on clinical response Injection Device Characteristics The GLP-1 RA injection devices consist of either a single-use or multi-dose pen that varies by needle size and thickness, which can be factors in predicting patient preference [125] (Table 4)