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The molecular mechanisms and signaling pathways by which GLP-1 improves sarcopenia.GLP-1 binds to GLP-1RA and exerts physiological effects through the PI3K/Akt and cAMP/PKA signaling pathways.GLP-1 mainly promotes muscle protein synthesis through the PI3K/Akt/mTORC1 pathway.The catabolism of muscle is mediated by specific transcription factors, such as FOXO proteins and NF-KB, and the activation of these transcription factors is triggered by extracellular stimuli or JAK-STAT signaling.GLP-1 can also improve mitochondrial function, reduce oxidative stress, and promote autophagy

Recommended Protein Sources: Poultry: Skinless chicken or turkey breasts are excellent lean protein options that can be prepared in a variety of healthy ways

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Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion

[DOI] [PubMed] [Google Scholar] 71.Ma B, Wang X, Ren H, Li Y, Zhang H, Yang M, et al

GLP-1 receptor agonists are a synthetic form of your bodys naturally occurring GLP-1 hormone, which is implicated in insulin release after eating