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Four hundred seven participants with obesity and a clinical and radiologic diagnosis of moderate knee osteoarthritis with at least moderate pain were randomly assigned to receive once-weekly subcutaneous semaglutide or placebo in a 2:1 ratio in addition to counseling on physical activity and a reduced-calorie diet

Sometimes youre worried about like a very clinical setting inside outpatient type doctors offices, it seems, but everyone kind of put you at ease and relaxed and, and, yeah, it just felt very comfortable.

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But what are these drugs exactly and do they live up to all the hype

Although treatment discontinuation is common among patients receiving tirzepatide or semaglutide for obesity, data quantifying specific reasons for discontinuation, including by discontinuation timing, remain limited
