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In the LOOK-AHEAD study, 5145 participants aged 4576 years (mean BMI 36 kg/m 2 ) with T2D were randomized to either calorie restriction or diabetes support and education intervention (controls) [33]

Notably, injection site reactions demonstrated significantly higher prevalence in female patients (p 65 years

Time from randomization to first composite kidney event, first composite major cardio-vascular event, and first all-cause death event were analyzed using Cox proportional hazards model, with flozins at baseline used for stratification

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It was the first major pharmaceutical company to sign a deal with the Trump administration to lower the price of its prescription drugs in the Medicaid program in exchange for three years of tariff relief