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Outcomes 15 studies involving 107 patients were assessed which suggested some benefit including potential resolution or reduction in hypoglycaemic episodes and/or symptoms and/or glucose stabilising effects in all cases treated with GLP-1 RMs (Table 2)

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This natural response can make continued weight loss slower and more gradual, even with medication

Patients must be prepared for the reality that they would need to take some kind of medication for the rest of their life if they intend to keep the weight off

In general, patients with preexisting endometrial hyperplasia should not receive long-term tamoxifen therapy