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doi: 10.1371/journal.pone.0172604 122 GrabenhorstFRollsETParrisBAdSouzaAA
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In controlled clinical studies as both monotherapy and combination therapy with metformin, pioglitazone, or rosiglitazone and metformin, the overall incidence of adverse reactions, hypoglycemia, and discontinuation of therapy due to clinical adverse reactions with JANUVIA were similar to placebo
