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Bridging the gap between guidelines and practice will require systemic interventions, including physician training, patient-centered care models, and devising research strategies such as national HF registries to understand and tailor therapeutic approaches from an Indian perspective.

To accommodate GLP-2 rather than GLP-1, GLP-2R fine-tunes the conformations of the extracellular parts of transmembrane helices (TMs) 1, 5, 7 and extracellular loop 1 (ECL1)

Novo Nordisk's semaglutide patents expire between 2026-2033 depending on formulation and jurisdiction

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