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[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Malavazos A.E., Iacobellis G., Dozio E., Basilico S., Di Vincenzo A., Dubini C., Menicanti L., Vianello E., Meregalli C., Ruocco C., et al

In the SURMOUNT 1 trial, tirzepatide at doses of 5 mg, 10 mg and 15 mg were evaluated against placebo, with pooled tirzepatide groups resulting in significant decreases in total cholesterol, LDL-C, VLDL-C, FFA, and triglycerides and an increase in HDL-C at week 72 of follow-up [35]