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Study finds that individuals who took GLP-1 agonists for a long duration had a lower risk of going on to develop more severe forms of liver disease, including cirrhosis and liver cancer.

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However, no retrospective epidemiological studies can provide definitive answers, and nausea, vomiting and diarrhoea remain the most clinically relevant adverse effects of these drugs, compromising long-term adherence.

GLP-1 medications like semaglutide reduce hunger and slow digestion, potentially making intermittent fasting easier to sustain

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Clinical Take-Home Messages "Maximize before you switch" may be a reasonable strategy