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Medical Condition Contrave is FDA-approved for weight management in people with a body mass index (BMI) of more than 30, or a BMI of more than 27 with another weight-related condition, like high blood pressure, Type 2 diabetes, or high cholesterol

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5 Mechanisms by which metformin acts through regulation of the gut microbiota 5.1 Acts by stabilizing the mucosal barrier of the GI tract The GI mucosal barrier with important physiological roles is a three-dimensional protective structure consisting of mechanical, chemical, immune and biological barriers

The slower transit time means more fermentation, more gas production, and more discomfort

When the GLP-1[RA] drugs are being sold to diabetic patients, thats a completely different story versus when the drug is used for weight management, Han explained
Why Its Especially Helpful for People with Diabetes