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10.1016/j.cell.2016.05.023 108 WyshamC.BlevinsT.ArakakiR.ColonG.GarciaP.AtissoC.et al (2014)

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rather, it may represent a normalisation of appetite signalling that many individuals with obesity have not experienced for years

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Theyre fascinating drugs for which scientists have already found many good uses, Standaert says, but that doesnt mean they cure everything. At this point, he says, I think we need to back up a little bit and ask ourselves, How do these GLP-1s work anyway? Sperling echoes the thought

Get the details: #MACE #PCSK9I To view or add a comment, sign in Evolocumab can help attenuate the elevated risk of major adverse cardiovascular events that individuals with obesity and atherosclerotic cardiovascular disease (ASCVD) face, according to a prespecified analysis from the FOURIER trial published in #JACC