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A meta-analysis of epidemiological studies revealed a higher incidence of inflammatory bowel disease in males, with a male-to-female ratio of 1.64:1 for Crohns disease and 1.29:1 for ulcerative colitis [64]

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The GLP-1 component delays stomach emptying, inhibits the release of needless glucagon, and promotes insulin release in a glucose-dependent manner

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The studies found sleep apnea patients on tirzepatide who weren't using a CPAP machine had 25 fewer breathing interruptions per hour compared with five fewer breathing disruptions among those taking a placebo