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Patients with a personal or family history of MTC or MEN2 should not receive these medications

GLP-1 signaling and appetite regulation GLP-1 (glucagon-like peptide-1) receptor agonists represent the most dramatic weight loss results of any peptide class

doi: 10.1016/j.ejphar.2022.175356

Breast Cancer: A 3047% Risk Reduction Among the most clinically significant findings was a real-world cohort study presented at ASCO 2026, which reported that women with Type 2 diabetes or obesity using GLP-1 receptor agonists experienced a 30 to 47% reduction in breast cancer risk compared to non-users

doi: 10.1126/scitranslmed.3007218, 30

Table 1 respectively