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Glucose-dependent mechanism minimizes hypoglycemia risk This pathway reduces glucose only when blood levels are high, offering a safer profile versus some other antidiabetic agents

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All therapeutic interventions should be accompanied by motivational support, strengthening patient perceptions about their own ability and self-efficacy to self-manage diabetes [224, 225]

While GLP-1 (7-36amide) and GLP-1 (737) are equally potent to stimulate the secretion of insulin and c-peptide [181], GLP-1 (137) has a much lower insulinotropic efficacy [[80], [81], [82]]

DOI: Published online: August 20, 2012 1 Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea