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Inadequate Therapeutic Response: Contact your healthcare provider if you experience minimal or no improvement in target outcomes after reaching your maintenance dose for 12-16 weeks

doi:10.1056/nejmoa2301972 9.Douros JD, Mowery SA, Knerr PJ

10.1210/jc.2019-00008 17 BerlierJ.KharroubiI.ZhangJ.Dalla ValleA.RiguttoS.MathieuM.et al (2015)

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So let's build a clinical strategy around that' I think that's a big mistake." It remains to be seen how all these startups will fare as more and more patients quit their weight-loss medications

Additionally, a clinically validated report presented at a major obesity conference showed an average weight loss of 16.5% after 18 months for those who continued into a second year