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Pfizer recently had to abandon its GLP-1 pill based on safety concerns, she writes

1 It is critical that effective treatment options exist to help patients tackle this problem

The study, conducted using electronic health records from the TriNetX network between 2017 and 2024, excluded patients with prior neurodegenerative or cerebrovascular conditions and used propensity score matching to balance baseline characteristics

EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis

These medications work by binding to and activating GLP-1 receptors throughout the body

7 The research opportunity connecting claims with real-world data The opportunity for manufacturers, researchers, and healthcare stakeholders is to bridge this data gap and gain a comprehensive view of the GLP-1 obesity treatment journey