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Removing them abruptly may lead to rebound eating

Conclusion This study highlights the importance of integrating the use of therapies with CV benefit into the treatment of people with T2D in accordance with clinical practice guidelines

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PGC1a, peroxisome proliferator activated receptor gamma coactivator 1 alpha

These fibres are fermented by beneficial bacteria into short-chain fatty acids such as butyrate and propionate, which activate receptors on intestinal L-cells responsible for GLP-1 secretion

Tirzepatide represents the step up when semaglutide results plateau or when insulin resistance is a primary concern given its GIP mechanism