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Description
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The FDA has approved glucagon-like peptide-1 (GLP-1) receptor agonists such as Liraglutide, Semaglutide, and the GLP-1/gastric inhibitory polypeptide (GIP) dual agonist Tirzepatide for the treatment of obesity
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The metabolic rate of GLP-1R KO mice was significantly slower than that of WT mice (p=0.0345, WT mice 0.023350.057mM/min, GLP-1R KO mice 0.019980.07mM/min)
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Combining Mounjaro (tirzepatide) and Ozempic (semaglutide) is not recommended because both medications target overlapping weight loss pathways
