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For instance, SURPASS-1 highlighted its effectiveness as a standalone therapy, showing significant reductions in HbA1c levels and notable weight loss [43]

You should contact your GP or healthcare team if you: Experience persistent or severe gastrointestinal symptoms that affect your quality of life Develop severe abdominal pain that could indicate pancreatitis Notice unexplained weight loss beyond expected therapeutic effects Experience any sudden changes in vision Have concerns about your cholesterol levels or cardiovascular risk Are planning pregnancy or become pregnant while taking Ozempic Experience any unexpected symptoms or side effects during treatment Suspected side effects should be reported via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

If you experience a suspected side effect from any medicine, report it via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk

mineralocorticoid receptor antagonists (MRAs)

When considering compounded GLP-1 options like semaglutide or tirzepatide, understanding your individual gastric physiology and genetic factors affecting appetite regulation may help provide context for a personalized safety conversation with your healthcare provider

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