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This GLP-1 analogue also exhibited immunomodulatory properties, enhancing the number of circulating iNKT cells and reducing the proportion of TNF-producing monocytes [151]

Gastric emptying and the personalized management of type 1 diabetes

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In preclinical studies, GLP-1R agonists have been demonstrated to improve hepatocyte mitochondrial function and hepatic insulin sensitivity [67], and reduce adipose tissue lipotoxicity both due to body-weight loss and mechanisms independent of body-weight reductions [68]
