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[Thus,] the scope of these drugs and the potential benefit of these drugs is likely to be much broader than what was originally described.

[2] Additional trials in type-2 diabetes and liver-fat conditions have also been reported

Dayabandara M, Hanwella R, Ratnatunga S, Seneviratne S, Suraweera C, de Silva VA

International Journal of Molecular Sciences, 2025 DOI: 10.3390/ijms262411774 #MultipleSclerosis #Neuroimmunology #Biomarkers #OCT #DisabilityProgression #ClinicalResearch #Neurology To view or add a comment, sign in Exploring extracellular vesicles as diagnostic tools in gutbrain axis disorders: in this concise review article, Patricia Maral da Costa, Reinaldo Barreto Ori at Federal University of Ceara and collaborators integrated microbial- and brain-derived extracellular vesicles within the framework of gutbrain axis disorders and proposed three translational diagnostic niches: microbial EVs as systemic indicators of dysbiosis and immune activation, brain-derived EVs as liquid biopsies of central nervous system pathology, and engineered or technologically captured EVs as platforms for point-of-care testing

16 On the other hand, the investigational use of GIPR agonists (GIPRAs) has not yielded similar advantages, partly because of a lack of understanding of GIP dose-response actions