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These medications work by curbing hunger, delaying stomach emptying, and controlling blood sugar levels

Weight loss on tirzepatide varies significantly between individuals due to metabolic, lifestyle, and genetic factors

However, the absence of prospective short- and long-term outcome data underscores the need for systematic investigation to define optimal timing, safety parameters, and oncologic efficacy of weight-loss interventions in this high-risk population.
Monotherapy showed higher AE rates

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