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[Google Scholar] 2.Dungan K, DeSantis A Glucagon-like peptide 1-based therapies for the treatment of type 2 diabetes mellitus

Fiber undergoes bacterial fermentation in the colon, producing short-chain fatty acids (SCFAs)particularly butyrate, propionate, and acetatewhich can stimulate L-cell GLP-1 secretion

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In clinical studies treatment with liraglutide was associated with an increase in HR (mean difference 7 bpm) and more serious cardiac adverse events (3% vs 10% for placebo and liraglutide, respectively) in chronic heart failure patients with and without type 2 diabetes (135)