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Liu T-h, Chen M-h, Zhang C-y, Xie T, Zhang S, Hao H, et al

for example, semaglutide has a half-life of approximately 7 days based on the dosage used (Ushakumari and Sladen 2024

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Zepbound (tirzepatide) was FDA-approved in November 2023 for chronic weight management in adults with obesity (BMI 30+) or overweight (BMI 27+) with a weight-related condition

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In reality, a plateau can reflect hydration shifts, digestion changes, sleep quality, stress, strength training, or normal metabolic adaptation