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2.2 Recommended Dosage The recommended dosage for PAXLOVID is 300 mg nirmatrelvir (two 150 mg tablets) with 100 mg ritonavir (one 100 mg tablet) with all 3 tablets taken together orally twice daily in the morning and at bedtime for 5 days

The most relevant data comes from a large phase 3 clinical trial (OASIS 4), published in the New England Journal of Medicine (2025)

Some common comorbidities include: diabetes mellitus and metabolic syndrome, arthritis, spondyloarthropathy, polycystic ovarian syndrome (PCOS), trisomy 21 (Down syndrome), and various cancers

Yoko Iwata has nothing to disclose

94.Overgaard RV, Hertz CL, Ingwersen SH, Navarria A, Drucker DJ

Some people responded strongly, others not at all
