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Therefore, DPP-4 inhibitors may have pleiotropic effects

They also appear able to enhance microvascular (!) blood flows in the muscle tissue, reduce muscle-produced inflammation, and enhance glucose and lipid metabolism in the muscles

During glucose regulation, activation of these receptors helps improve the function of -cells and protect the pancreas, enhancing insulin secretion and better controlling blood sugar levels

In patients receiving GLP-1 RAs for diabetes, the most obvious harm from holding them is poorly controlled blood glucose

Current human studies have not shown an increased overall cancer risk with GLP-1 medications

This dual agonist approach enhances its potential for glycemic control and weight loss in patients with type 2 diabetes