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Congratulations to the authorsAmalie Dyrelund Broks, Mads Brner Kristensen,Bolette Hartmann,Knud Josefsen,Jens Juul Holst, and Tue Kragstrupfor theirwork - and forhelping chartexciting new research avenues and novel treatment approaches for patients. You canfindthe paper, Detection of GLP-1 and DPP-4 in synovial fluid: implications for therapeutical strategies in arthriti, here: #GLP1 #Rheumatology #Arthritis #TranslationalResearch #ClinicalResearch #Inflammation

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Given the promising results in pre-clinical models (even in the absence of T2D), a unique mechanism of action and multiple age-related reduced disease risks that have been reported with acarbose, support for clinical trials with acarbose focusing on aging-related outcomes and incorporating biological sex, age at treatment initiation, and T2D-dependence within the design is warranted.