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In the subpopulation of participants from the China region (75.2% of trial participants), reductions in HbA 1c and body weight from baseline to week 26 were similar to those seen in the overall population

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They work by controlling blood sugar levels through similar mechanisms, like increasing insulin release, delaying gastric emptying, and suppressing glucagon (which stimulates blood sugar)

doi: 10.1093/brain/awx044

High-dose studies show notable HbA1c reductions, significant weight loss, and improvements in lipid profiles and blood pressure, supporting its role in multi-hormone metabolic investigations
