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And I think that needs to be continued as we progress into using these medications for longer periods of time, to ensure that we know the entirety of the risks and the benefits of them

Real-world data cited in the paper suggest roughly half of patients discontinue treatment within a year of starting it a rate far higher than the trials, with their closer supervision, capture

Although this reduction may appear modest, its long-term impact in preventing diabetes-related complications is substantial

Amini MR, Sheikhhossein F, Talebyan A, Bazshahi E, Djafari F, Hekmatdoost A

doi: 10.1016/S2213-8587(15)00436-2 59 FrandsenCSDejgaardTFHolstJJAndersenHUThorsteinssonBMadsbadS

The side effect comparison between semaglutide and tirzepatide shows broadly similar profiles with slightly lower severity for semaglutide at equivalent therapeutic doses