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Umpierrez GE, Cardona S, Chachkhiani D et al (2018) A randomized controlled study comparing a DPP4 inhibitor (linagliptin) and basal insulin (glargine) in patients with type 2 diabetes in long-term care and skilled nursing facilities: Linagliptin-LTC trial

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demonstrated that liraglutide modulates the composition of obesity-associated gut microbiota, such as Escherichia coli , markedly restructuring the microbial community and reshaping bacterial taxa linked to body weight regulation, thereby contributing to weight reduction ( Nevertheless, there are also some contradictory results