does semaglutide work if you are not obese Who Qualifies for Ozempic Weight Loss? Why Am I Not Losing

Focus on hunger and fullness cues rather than calorie counting

The key difference lies in how they work: semaglutide focuses solely on GLP-1 receptors , while tirzepatide targets both GLP-1 and GIP receptors

She was not obese (height 158 cm, weight 50 kg), but had been using GLP1-RAs for weight loss for a year on the recommendation of the manager of her workplace

Patients commonly report significant improvements in appetite control, reduced cravings, and smaller portion sizes, leading to steady progress

The downstream IGF-1 rise mobilises lipid from visceral depots preferentially over subcutaneous fat, which is why the compound remains of interest for VAT-isolated body-composition protocols

In this comparison, Ozempic generally provides stronger A1C reduction, while Jardiance is often preferred for its cardiovascular and kidney protection benefits