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Physiological factors affecting drug toxicity

Pharmacology studies have demonstrated that tirzepatide's effect on gastric emptying is most pronounced during the first few weeks of treatment and with dose escalations

And so as a result because you dont have to the digestive system doesnt have to be so responsive to the messages of the vagus nerve, which if theyre design, if our own hormones are designed like a motion detector, I would argue its like theyre experiencing a stampede in front of the motion detector, Like all day long and and even all night long

If thats the case, just be prepared to redo the gradual dosage increase to minimize side effects

For example, Finan et al have developed a stable GLP-1-estradiol conjugate (245)