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Supported by NZD $30 million of funding and over ten years of research by the New Zealand Institute for Plant and Food Research Limited, a New Zealand government-owned Crown Research Institute

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### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

Understanding who may be at higher riskbased on medical history, biomarkers, and genetic predispositionscan help patients and providers make more informed treatment decisions