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Glucagon-like peptide 1 (GLP-1) is a cleavage product of the pre-proglucagon gene which is expressed in the -cells of the pancreas, the L-cells of the intestine, and neurons located in the caudal brainstem and hypothalamus

Semaglutide was originally developed for type 2 diabetes, but clinical evidence now supports its use for chronic weight management in people without diabetes who have overweight or obesity

This review examines the effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) on different heart failure phenotypes with preserved ejection fraction

Studies show neuroprotective effects in Alzheimer's and Parkinson's disease models through reduced inflammation, enhanced neuronal survival, and improved cognitive function

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