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[ 60 ] Beyond these pharmacokinetic factors, at the cellular level, recent studies have begun to uncover how obesity contributes to chemotherapy resistance, particularly through the activation of pathways like those involving YAP, recognized as a critical energy sensor, interacts with metabolic processes that are pivotal in cancer metabolism

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(2023) in The Lancet showed clinically meaningful HbA1c and body-weight reductions versus dulaglutide in the active-comparator arm

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Benzin J, Gouverneur A, Mathieu C, et al
