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However, its future trajectory is far from linear as many uncertainties remain, e.g., acceptance of obesity as a chronic disease, budget impact faced by payers and health systems willingness and ability to pay, the readout of further cardiovascular outcomes trials after the high profile results of 2023s SELECT trial for Wegovy, or new entrants challenging first generation therapies with alternative mechanisms of action (MoA) to address shortcomings such as gastrointestinal tolerability, current drugs being injectables, or the durability and quality of weight loss which distinguishes between fat and lean body mass

Genetic factors and biomarkers may help contextualize why some patients experience musculoskeletal discomfort while others don't, supporting more informed conversations with healthcare

Discover how these popular medications may impact your vein health, including their effects on varicose veins, chronic venous insufficiency, circulation, and blood clot